Departure time
Airlines
Fares are the lowest prices found recently and can change when you click through. You book on the airline's or travel agency's website. AirTriply may earn a commission at no extra cost to you.
Lowest fare$238
Cheapest monthNovember 2026
Typical flight time4h 53m
Direct flightsYes
Lowest fare by month
Airlines on this route
Frequently asked questions
What is the cheapest month to fly from Guayaquil to Santiago?
November 2026 has had the lowest recent fares, from $238 one way.
How long is the flight from Guayaquil to Santiago?
A typical flight takes about 4h 53m.
Are there direct flights from Guayaquil to Santiago?
Yes. Direct flights have been found recently from $238.
Where do I book my ticket?
AirTriply compares fares from airlines and travel agencies. When you choose a deal, you book on the seller's own website.
Popular routes
Guayaquil → QuitoGuayaquil → Galapagos IslandsGuayaquil → BogotaGuayaquil → MedellinGuayaquil → Panama CityGuayaquil → MiamiGuayaquil → New YorkGuayaquil → Fort LauderdaleGuayaquil → LimaGuayaquil → NewburghGuayaquil → Sao PauloGuayaquil → Rio de JaneiroGuayaquil → Mexico CityCheap flights to SantiagoCheap flights from Santiago
