Cheap flights from Medellin to Santiago

Compare flight prices from Medellin to Santiago across airlines and travel sites, see the cheapest month and day to fly, then book direct with the seller.

Lowest fare$190
Cheapest monthDecember 2026
Typical flight time6h 12m
Direct flightsYes

Lowest fare by month

$258November 2026
$190December 2026
–January 2027
–February 2027
–March 2027
–April 2027

Airlines on this route

Frequently asked questions

What is the cheapest month to fly from Medellin to Santiago?

December 2026 has had the lowest recent fares, from $190 one way.

How long is the flight from Medellin to Santiago?

A typical flight takes about 6h 12m.

Are there direct flights from Medellin to Santiago?

Yes. Direct flights have been found recently from $190.

Where do I book my ticket?

AirTriply compares fares from airlines and travel agencies. When you choose a deal, you book on the seller's own website.

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