Departure time
Airlines
Fares are the lowest prices found recently and can change when you click through. You book on the airline's or travel agency's website. AirTriply may earn a commission at no extra cost to you.
Lowest fare$233
Cheapest monthNovember 2026
Typical flight time2h 16m
Direct flightsYes
Lowest fare by month
Airlines on this route
Frequently asked questions
What is the cheapest month to fly from Panama City to Guayaquil?
November 2026 has had the lowest recent fares, from $233 one way.
How long is the flight from Panama City to Guayaquil?
A typical flight takes about 2h 16m.
Are there direct flights from Panama City to Guayaquil?
Yes. Direct flights have been found recently from $233.
Where do I book my ticket?
AirTriply compares fares from airlines and travel agencies. When you choose a deal, you book on the seller's own website.
Popular routes
Panama City → Bocas Del ToroPanama City → DavidPanama City → Mexico CityPanama City → CartagenaPanama City → San JosePanama City → QuitoPanama City → CuencaPanama City → San SalvadorPanama City → CancunPanama City → LimaPanama City → San Andres IslandPanama City → Sao PauloPanama City → BogotaCheap flights to GuayaquilCheap flights from Guayaquil
